abstract：OBJECTIVE:To assess the extent to which prostate HistoScanning (PHS), a new ultrasound-based technology that uses computer-aided analysis to quantify tissue disorganization induced by malignant processes, can identify and characterize foci of prostate cancer compared with step-sectioned radical prostatectomy (RP) speci...

journal_title：BJU international

authors： Braeckman J,Autier P,Garbar C,Marichal MP,Soviany C,Nir R,Nir D,Michielsen D,Bleiberg H,Egevad L,Emberton M

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To evaluate whether the degree of preoperative bladder trabeculation in neurogenic bladder (NB) patients is a marker of significant outlet resistance. If so, severe trabeculation may obviate the need for concomitant bladder outlet procedure (BOP) during augmentation cystoplasty (AC). PATIENTS AND METHODS:We ...

journal_title：BJU international

authors： Khoury AE,Dave S,Peralta-Del Valle MH,Braga LH,Lorenzo AJ,Bägli D

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To present our experience with bladder cancer among a renal transplant population and to review critically the relevant literature. PATIENTS AND METHODS:In all, 1865 renal graft recipients were followed for a mean (SD) of 6.5 (5) years. Seven recipients (all men) developed a urothelial bladder tumour. The s...

journal_title：BJU international

authors： Kamal MM,Soliman SM,Shokeir AA,Abol-Enein H,Ghoneim MA

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between adult male circumcision and sexual satisfaction and function in men, as observational studies on the effect of adult male circumcision on sexual satisfaction show conflicting results. SUBJECTS AND METHODS:We investigated self-reported sexual satisfaction and function a...

journal_title：BJU international

authors： Kigozi G,Watya S,Polis CB,Buwembo D,Kiggundu V,Wawer MJ,Serwadda D,Nalugoda F,Kiwanuka N,Bacon MC,Ssempijja V,Makumbi F,Gray RH

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To ascertain the prevalence of lower urinary tract symptoms (LUTS) and urinary incontinence (UI) in Canada, using a cross-Canada telephone survey, as there is a wide discrepancy in the reported prevalence of these conditions. SUBJECTS AND METHODS:A random survey with a standardized questionnaire was conducte...

journal_title：BJU international

authors： Herschorn S,Gajewski J,Schulz J,Corcos J

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To investigate cell division cycle 91-like 1 (CDC91L1; also called phosphatidylinositol glycan class U, PIG-U) expression in bladder cancer at both the mRNA and protein levels, and to study its clinical and prognostic significance, as CDC91L1 was recently identified as a new oncogene in human bladder cancer a...

journal_title：BJU international

authors： Shen YJ,Ye DW,Yao XD,Trink B,Zhou XY,Zhang SL,Dai B,Zhang HL,Zhu Y,Guo Z,Wu G,Nagpal J

更新日期：2008-01-01 00:00:00

abstract：:The first two reviews are from the same unit in Germany and describe the well-known but still much discussed ways of improving the prognosis of patients undergoing cystectomy for bladder cancer. The authors review the roles of lymph node dissection and perioperative chemotherapy, and draw conclusions which will be of ...

journal_title：BJU international

authors： Suttmann H,Kamradt J,Lehmann J,Stöckle M

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of sildenafil on noradrenaline- and potassium-induced contractions of isolated human seminal vesicles (SVs), as premature ejaculation is a relatively common male sexual dysfunction that currently lacks an adequate therapy, and recent in vitro tests showed that sildenafil induces rel...

journal_title：BJU international

authors： Gajar SA,Tano T,Resende AC,Bitencourt JA,de Lemos Neto M,Damião R,Criddle DN,Soares de Moura R

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To assess the significance of viable tumour in the prostate of patients with metastatic androgen-independent prostate cancer (AIPC). PATIENTS AND METHODS:We evaluated the clinicopathological features, including follow-up, of 40 men with metastatic AIPC who had a transrectal biopsy of the prostate. RESULTS:P...

journal_title：BJU international

authors： Aragon-Ching JB,Gillespie J,Price DK,Chuaqui R,Rodriguez-Canales J,Steinberg SM,Dahut WL,Figg WD

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:To describe a technique for transurethral tumour inoculation, bioluminescence imaging (BLI) and validation of this approach using ex vivo magnetic resonance imaging (MRI), as a reproducible and quantifiable model of orthotopic bladder cancer is required to enable preclinical pharmacological studies of intrav...

journal_title：BJU international

authors： Hadaschik BA,Black PC,Sea JC,Metwalli AR,Fazli L,Dinney CP,Gleave ME,So AI

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between the presence of high-grade prostatic intraepithelial neoplasia (HGPIN) in retropubic radical prostatectomy (RP) specimens and cancer-specific outcomes, including pathological variables and biochemical disease-free survival (bDFS), as HGPIN shares many histopathological char...

journal_title：BJU international

authors： Pierorazio PM,Lambert SM,Matsukhani M,Sprenkle PC,McCann TR,Katz AE,Olsson CA,Benson MC,McKiernan JM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To investigate the morbidity and mortality after radical prostatectomy (RP) in relation to the numbers of RPs carried out at individual hospitals, as recent studies of complex surgery report worse outcomes in low-volume hospitals, and there has been a large increase in RPs for localized prostate cancer. METH...

journal_title：BJU international

authors： Judge A,Evans S,Gunnell DJ,Albertsen PC,Verne J,Martin RM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To investigate the correlation of transient receptor potential vanilloid subfamily 1 (TRPV1) mRNA expression levels and the clinical outcome of intravesical resiniferatoxin treatment in patients with idiopathic detrusor overactivity (IDO), as such treatment with vanilloids can be effective for DO. PATIENTS ...

journal_title：BJU international

authors： Liu HT,Kuo HC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of the application of autologous myoblasts and fibroblasts for treating female stress urinary incontinence (SUI) after a follow-up of >/=1 year. PATIENTS AND METHODS:In all, 123 women with SUI (aged 36-84 years) were treated with transurethral ultrasonography-guided injectio...

journal_title：BJU international

authors： Mitterberger M,Marksteiner R,Margreiter E,Pinggera GM,Colleselli D,Frauscher F,Ulmer H,Fussenegger M,Bartsch G,Strasser H

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To present our experience of cavernous nerve graft reconstruction, using an autologous nerve vein-guide technique, to restore potency. PATIENTS AND METHODS:Prostate cancers frequently require radical resection involving one or both cavernous nerves that usually results in erectile dysfunction; nerve grafting...

journal_title：BJU international

authors： Fujioka M,Tasaki I,Kitamura R,Yakabe A,Hayashi M,Matsuya F,Miyaguchi T,Tsuruta J

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of a transportable extracorporeal shock wave lithotripsy (ESWL) machine, the Modulith SLX-F2(TM) (Storz Medical Italia, Rome, Italy), in the management of solitary urinary calculi. PATIENTS AND METHODS:The study included 233 patients (mean age 51 years; 172 male, 61 female) ...

journal_title：BJU international

authors： De Sio M,Autorino R,Quarto G,Mordente S,Giugliano F,Di Giacomo F,Neri F,Quattrone C,Sorrentino D,De Domenico R,D'Armiento M

更新日期：2007-11-01 00:00:00

abstract：:OBJECTIVE To investigate the incidence of new-onset diabetes mellitus (NODM) and of worsening glycaemic control in established DM after starting androgen-deprivation therapy (ADT) for prostate cancer, as ADT is associated with altered body composition, potentially influencing insulin sensitivity. PATIENTS AND METHODS ...

journal_title：BJU international

authors： Derweesh IH,Diblasio CJ,Kincade MC,Malcolm JB,Lamar KD,Patterson AL,Kitabchi AE,Wake RW

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between glycogen content in bladder detrusor tissue and historical bladder function in a guinea-pig model of partial bladder outlet obstruction (PBOO). MATERIALS AND METHODS:In male immature guinea pigs PBOO was created with a silver ring around the proximal urethra; a control grou...

journal_title：BJU international

authors： de Jong BW,Wolffenbuttel KP,Arentshorst ME,Lodder P,Kok DJ

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...

journal_title：BJU international

authors： Danforth TL,Lane BR,Novick AC

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To report our 5-year experience with laparoscopic and percutaneous cryoablation (LCA and PCA) for managing small renal masses. PATIENTS AND METHODS:We retrospectively analysed patients undergoing LCA and PCA between October 2000 and March 2006 at our institution. After approval from the Institutional Review ...

journal_title：BJU international

authors： Bandi G,Wen CC,Hedican SP,Moon TD,Lee FT Jr,Nakada SY

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To identify and describe changes to the motor component of the motor/sensory system, which contributes to sensation during the filling phase of the micturition cycle, as a result of surgically induced bladder pathology, i.e. damage to the bladder neck and outlet obstruction. MATERIALS AND METHODS:Adult male ...

journal_title：BJU international

authors： de Jongh R,van Koeveringe GA,van Kerrebroeck PE,Markerink-van Ittersum M,de Vente J,Gillespie JI

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To assess the clinical pattern of progression and prostate-specific antigen doubling time (PSA-DT) after exposure to docetaxel-based chemotherapy in patients with androgen-independent prostate cancer (AIPC). PATIENTS AND METHODS:Fifty-five patients received docetaxel-based chemotherapy; data were collected r...

journal_title：BJU international

authors： Sella A,Sternberg C,Kovel S,Yarom N,Skoneczna I

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:To assess the activity of baclofen, a potent gamma-aminobutyric acid-ergic agonist, against dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS) in a clinical trial, as DV is a leading cause of LUTS in women, but there is no effective treatment. PATIENTS AND METHODS:We conducted a randomized d...

journal_title：BJU international

authors： Xu D,Qu C,Meng H,Ren J,Zhu Y,Min Z,Kong Y

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of low-dose rate prostate brachytherapy on the sexual health of men with > or = 7 years of prospective evaluation and optimum sexual function before treatment. PATIENTS AND METHODS:In all, 223 patients with T1b to T3a prostate cancer and a median (range) age of 66 (50-82) years were tr...

journal_title：BJU international

authors： Cesaretti JA,Kao J,Stone NN,Stock RG

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of patient age on the stone-free rate (SFR) in patients with urinary calculi treated by extracorporeal shockwave lithotripsy (ESWL). PATIENTS AND METHODS:In all, 2192 solitary radio-opaque urinary stones of 5-15 mm were identified in adult patients receiving primary ESWL. Patients ...

journal_title：BJU international

authors： Ng CF,Wong A,Tolley D

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of lactate dehydrogenase (LDH), a tumour marker that is frequently elevated at diagnosis and relapse of testicular germ cell tumours (TGCTs), in the follow-up of TGCTs for detecting tumour relapse, as it has role as a prognostic factor but its role in follow-up is less certain. PATIEN...

journal_title：BJU international

authors： Venkitaraman R,Johnson B,Huddart RA,Parker CC,Horwich A,Dearnaley DP

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To determine if baseline characteristics, treatment efficacy, psychosocial outcomes or tolerability were associated with patient preference for sildenafil citrate (sildenafil) or tadalafil for treating erectile dysfunction (ED) in men naive to phosphodiesterase 5 inhibitor therapy. PATIENTS AND METHODS:In a...

journal_title：BJU international

authors： Eardley I,Montorsi F,Jackson G,Mirone V,Chan ML,Loughney K,Vail GM,Beardsworth A

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To review recently published data on emphysematous cystitis (EC), a potentially life-threatening condition characterized by air within the bladder wall, and that most typically affects middle-aged diabetic women. METHODS:All articles published in English between 1956 and 2006 were identified using a Medline ...

journal_title：BJU international

authors： Thomas AA,Lane BR,Thomas AZ,Remer EM,Campbell SC,Shoskes DA

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To evaluate peri-operative peripheral and renal venous plasma levels of vascular endothelial growth factor (VEGF), platelet-derived growth factor type BB (PDGF-BB), transforming growth factor (TGF)-beta1, endostatin, and thrombospondin-1 (TSP-1) in relation to pathological variables and prognosis, as pro- and...

journal_title：BJU international

authors： Klatte T,Böhm M,Nelius T,Filleur S,Reiher F,Allhoff EP

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To determine whether health-insurance status might result in more localized stage at presentation, more favourable stage at surgery and in a lower rate of biochemical recurrence (BCR), in patients diagnosed with prostate cancer and treated with radical prostatectomy (RP), as despite uninhibited access to heal...

journal_title：BJU international

authors： Gallina A,Karakiewicz PI,Chun FK,Briganti A,Graefen M,Montorsi F,Walz J,Jeldres C,Erbersdobler A,Salonia A,Suardi N,Dehò F,Schlomm T,Scattoni V,Haese A,Heinzer H,Valiquette L,Rigatti P,Huland H

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To explore the predictors of the quality of marriage of men with prostate cancer, as being diagnosed with prostate cancer affects the quality of life of the man and his partner, and while some aspects are known about the impact of the disease and its treatments on the man's quality of life, less is known abou...

journal_title：BJU international

authors： Sunny L,Hopfgarten T,Adolfsson J,Steineck G

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To assess reports supporting the novel and comprehensive evidence-based pathway for radical prostatectomy (RP), as collaborative-care pathways have helped to optimize management of patients treated with RP and such clinical pathways provide an ideal framework for constructing an original evidence-based pathwa...

journal_title：BJU international

authors： Kaufman MR,Baumgartner RG,Anderson LW,Smith JA Jr,Chang SS,Herrell SD,Cookson MS

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine the concentration of nitric oxide (NO) and the location and change in the expression of NO synthase (NOS) isoforms in the testes of subfertile men with varicocele, and to compare the NO concentration or NOS expression with clinical variables, to determine the role of NO on the pathophysiology of ...

journal_title：BJU international

authors： Shiraishi K,Naito K

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To describe a clinical subtype of urinary incontinence (UI) after a stroke, i.e. with impaired awareness of the need to void (IA-UI), and to compare it to urge UI after a stroke for the risk factors and medium-term outcome. PATIENTS AND METHODS:In a consecutive sample of 315 hospitalized stroke patients who ...

journal_title：BJU international

authors： Pettersen R,Stien R,Wyller TB

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of oxidized cellulose, Surgicel(TM) (Johnson & Johnson Medical, New Brunswick, NJ, USA) for patching defects in the tunica albuginea in a rabbit model, with a future application to correct chordee. MATERIALS AND METHODS:The study comprised nine New Zealand white male rabbits; a recta...

journal_title：BJU international

authors： El-Assmy A,Eassa W,El-Hamid MA,Nour EM,Hafez AT

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine whether the predictive value of isolated high-grade prostatic intraepithelial neoplasia (HGPIN) for an unsampled prostate cancer on an extended biopsy is lower due to more thorough prostate sampling, and whether the proportion of cores with HGPIN is associated with prostate cancer, as isolated HG...

journal_title：BJU international

authors： Akhavan A,Keith JD,Bastacky SI,Cai C,Wang Y,Nelson JB

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To illustrate the ultrastructural fibre composition of the rat cavernosal nerve at serial levels, from its origin in the main pelvic ganglion to its termination in the corpus cavernosum of the distal penile shaft, and to develop a technique that permits repeated electrophysiological recording from the fibres ...

journal_title：BJU international

authors： Schaumburg HH,Zotova E,Cannella B,Raine CS,Arezzo J,Tar M,Melman A

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To investigate the detection rate and extent of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical glands (AG) suspicious for prostate cancer, and the cancer risk in subsequent biopsies, diagnosed by a first 24-core saturation biopsy, as although the optimum extent of biopsy is controversial ...

journal_title：BJU international

authors： Schoenfield L,Jones JS,Zippe CD,Reuther AM,Klein E,Zhou M,Magi-Galluzzi C

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of a selective type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor, IC486051, on bladder activity in normal rats and those with and bladder outlet obstruction (BOO), as inhibition of PDE4 leads to elevation of intracellular cAMP levels and relaxation of smooth muscle. MATER...

journal_title：BJU international

authors： Nishiguchi J,Kwon DD,Kaiho Y,Chancellor MB,Kumon H,Snyder PB,Yoshimura N

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To measure dihydropyrimidine dehydrogenase (DPD), an enzyme involved in the metabolism of 5-fluorouracil (5-FU), expression in prostate cancer and determine whether 5-chloro-2,4-dihydroxypyridine (CDHP), a potent inhibitor of DPD, enhances the antitumoral activity of 5-FU against prostate cancer. PATIENTS, M...

journal_title：BJU international

authors： Li Y,Mizutani Y,Shiraishi T,Nakamura T,Mikami K,Takaha N,Okihara K,Kawauchi A,Sakai T,Miki T

更新日期：2007-03-01 00:00:00